Endogenous and Exogenous Depression: Symptoms, Causes, and Treatments

Psychiatrists and psychologists once used the terms endogenous and exDogenous to classify Depression. Endogenous means "arising internally," and Exogenous indicates "arising from an external source." While these terms are no longer used to diagnose Depression, they can still be helpful in understanding the different causes of the condition.

Endogenous vs. Exogenous Depression: A Closer Look

Here's a more in-brain look at the differences between Endogenous and Exogenous Depression:

<b>Endogenous Depression:</b> results from a combination of genetics, brain chemical imbalances, and other internal factors. It typically includes symptoms such as low Mood, Fatigue, Difficulty Concentrating, and changes in appetite or sleep patterns.

<b>Exogenous Depression:</b> Triggered by life events or stressors such as a loss, a relationship breakup, or a traumatic experience. It often includes symptoms such as low Mood, Difficulty Sleeping, and changes in appetite or weight.

Symptoms

While both types of Depression share common symptoms, here are some differences that may be helpful in distinguishing between them:

Endogenous Depression Symptoms:

• Feeling sad or hopeless for no apparent reason.
• Difficulty concentrating or making decisions.
• Fatigue or low energy.
• Guilt or feelings of worthlessness.
• Suicidality

Exogenous Depression Symptoms:

• Difficulty concentrating or making decisions.
• Fatigue or low energy.
• Guilt or feelings of worthlessness.
• Difficulty adjusting to major life changes or significant stressors, such as a loss or a significant life change.

Causes

Endogenous Depression:

• Genetics
• Family history of Depression or other mental health conditions.
• Hormonal changes, such as those during menopause or childbirth.
• Medical conditions or medications.
• Nutrition deficiencies
• Environmental stressors

Exogenous Depression:

• Traumatic life events, such as a loss, a relationship breakup, or a natural disasters.
• Significant life changes, such as starting a new job or moving to a new place
• Relationship problems, such as a Divorce or Separation.
• Work-related issues, such as Unemployment.
• Medical conditions, such as a cancer Diagnosis or a Heart Attack.

Diagnosis

A mental health professional will use a combination of factors to diagnose Depression. This may include:

• A personal and family history
• A physical examination
• lab tests
• Psychological testing

The type of Depression you are diagnosed with will determine how your treatment plan is developed.

Treatments

Treatment for both endogenous and Exogenous Depression typically includes a combination of Medication and Psychotherapy.

Medication:

• Antidepressants, such as Selective Serotonin Reuptake Inhibitors (SSRIs) or Serotonin-Norepinephrine Reuptake Inhibitors (SNRIs) can be effective in relieving symptoms of Depression.
• Antipsychotics or Mood Stabilizers may be added to the treatment plan for individuals with severe or Bipolar Depression.

Psychotherapy:

• Cognitive Behavioral therapy (CBT)
• Interpersonal Psychotherapy ( Psychodynamic therapy Dialectical Behavioral therapy (DBT)

These therapies can help people to understand the causes of their Depression, develop coping skills, and change unhealthy thinking patterns and behaviors.

Outlook

Depression is a serious condition, but it can be managed with the right treatment. Many people with Depression are able to recover fully and live full, happy lives.

If you are think you might be depressed, don't hesitate to reach out to a mental health professional for help.